This is an old news(November 2005), but sound interesting to me.
A Palm OS programmer Dmitry Grinberg, hack the Palm TX hardware and add a microphone to it. Check it in palminfocenter. there is a video you can download from here(avi, 4.2MB). Don't know how true it is.
So you can't run a skype on Palm TX because it don't even have a microphone build in.Link:-
There is some picture, before and after.